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Pre-organized structure of viral DNA at the binding-processing site of HIV-1 integrase
The integration of the human immunodeficiency virus type 1 DNA into the host cell genome is catalysed by the viral integrase (IN). The reaction consists of a 3′-processing [dinucleotide released from each 3′ end of the viral long terminal repeat (LTR)] followed by a strand transfer (insertion of the...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2005
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1074723/ https://ncbi.nlm.nih.gov/pubmed/15814814 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki346 |
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