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Increased glutamate synaptic transmission in the nucleus raphe magnus neurons from morphine-tolerant rats

Currently, opioid-based drugs are the most effective pain relievers that are widely used in the treatment of pain. However, the analgesic efficacy of opioids is significantly limited by the development of tolerance after repeated opioid administration. Glutamate receptors have been reported to criti...

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Detalhes bibliográficos
Main Authors: Bie, Bihua, Pan, Zhizhong Z
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1074357/
https://ncbi.nlm.nih.gov/pubmed/15813995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-1-7
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