Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9

Histone H3 Lys 9 (H3-K9) methylation is a crucial epigenetic mark for transcriptional silencing. G9a is the major mammalian H3-K9 methyltransferase that targets euchromatic regions and is essential for murine embryogenesis. There is a single G9a-related methyltransferase in mammals, called GLP/Eu-HM...

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Detalhes bibliográficos
Main Authors: Tachibana, Makoto, Ueda, Jun, Fukuda, Mikiko, Takeda, Naoki, Ohta, Tsutomu, Iwanari, Hiroko, Sakihama, Toshiko, Kodama, Tatsuhiko, Hamakubo, Takao, Shinkai, Yoichi
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2005
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1074319/
https://ncbi.nlm.nih.gov/pubmed/15774718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1284005
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