Identification of OmpT as the Protease That Hydrolyzes the Antimicrobial Peptide Protamine before It Enters Growing Cells of Escherichia coli

The influence of extracytoplasmic proteases on the resistance of Escherichia coli to the antimicrobial peptide protamine was investigated by testing strains with deletions in the protease genes degP, ptr, and ompT. Only ΔompT strains were hypersusceptible to protamine. This effect was abolished by p...

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Bibliografische Detailangaben

Veröffentlicht in:	J Bacteriol
Hauptverfasser:	Stumpe, Stefan, Schmid, Roland, Stephens, Daren L., Georgiou, George, Bakker, Evert P.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1998
Schlagworte:	Cell Surfaces
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC107389/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9683502/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.180.15.4002-4006.1998
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