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Identification of OmpT as the Protease That Hydrolyzes the Antimicrobial Peptide Protamine before It Enters Growing Cells of Escherichia coli

The influence of extracytoplasmic proteases on the resistance of Escherichia coli to the antimicrobial peptide protamine was investigated by testing strains with deletions in the protease genes degP, ptr, and ompT. Only ΔompT strains were hypersusceptible to protamine. This effect was abolished by p...

詳細記述

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書誌詳細
出版年:J Bacteriol
主要な著者: Stumpe, Stefan, Schmid, Roland, Stephens, Daren L., Georgiou, George, Bakker, Evert P.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 1998
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC107389/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9683502/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.180.15.4002-4006.1998
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