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The Carboxyl Terminus of VEGFR-2 Is Required for PKC-mediated Down-Regulation
Vascular endothelial growth factor receptor-2 (VEGFR-2/Flk-1) is a receptor tyrosine kinase (RTK) whose activation regulates angiogenesis. The regulatory mechanisms that attenuate VEGFR-2 signal relay are largely unknown. Our study shows that VEGFR-2 promotes phosphorylation of c-Cbl, but activation...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1073687/ https://ncbi.nlm.nih.gov/pubmed/15673613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-08-0749 |
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