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Postprenylation CAAX Processing Is Required for Proper Localization of Ras but Not Rho GTPases
The CAAX motif at the C terminus of most monomeric GTPases is required for membrane targeting because it signals for a series of three posttranslational modifications that include isoprenylation, endoproteolytic release of the C-terminal– AAX amino acids, and carboxyl methylation of the newly expose...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The American Society for Cell Biology
2005
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1073645/ https://ncbi.nlm.nih.gov/pubmed/15659645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-11-0960 |
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