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Ikaros integrates endocrine and immune system development

Ikaros transcription factors are essential regulators of lymphopoiesis and the development of the immune system. We now show that Ikaros is expressed in hormone-producing pituitary corticomelanotroph cells, where it binds the proopiomelanocortin promoter and regulates endogenous gene expression. Los...

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Detalles Bibliográficos
Main Authors: Ezzat, Shereen, Mader, Rene, Yu, ShunJiang, Ning, Terry, Poussier, Philippe, Asa, Sylvia L.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1070405/
https://ncbi.nlm.nih.gov/pubmed/15841184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200522486
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