Numb Proteins Specify Asymmetric Cell Fates via an Endocytosis- and Proteasome-Independent Pathway

Numb proteins are evolutionarily conserved signaling molecules that make the daughter cells different after asymmetric divisions by segregating to only one daughter. They contain distinct binding motifs for α-adaptin (α-Ada) and proteins with Eps15 homology (EH) domains, which regulate endocytosis,...

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Bibliografski detalji
Glavni autori: Tang, Haiyan, Rompani, Santiago B., Atkins, Joshua B., Zhou, Yan, Osterwalder, Thomas, Zhong, Weimin
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2005
Teme:
Signal Transduction
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1069617/
https://ncbi.nlm.nih.gov/pubmed/15798180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.8.2899-2909.2005
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