17β-Estradiol Inhibits Inflammatory Gene Expression by Controlling NF-κB Intracellular Localization

Estrogen is an immunoregulatory agent, in that hormone deprivation increases while 17β-estradiol (E(2)) administration blocks the inflammatory response; however, the underlying mechanism is still unknown. The transcription factor p65/relA, a member of the nuclear factor κB (NF-κB) family, plays a ma...

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Bibliografiske detaljer
Main Authors: Ghisletti, Serena, Meda, Clara, Maggi, Adriana, Vegeto, Elisabetta
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Gene Expression
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1069609/
https://ncbi.nlm.nih.gov/pubmed/15798185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.8.2957-2968.2005
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