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17β-Estradiol Attenuates Hematoma Expansion through ERα/Sirt1/NF-κB Pathway in Hyperglycemic Intracerebral Hemorrhage Mice

BACKGROUND AND PURPOSE: 17β-estradiol (E2) has been reported to reduce bleeding and brain injury in experimental intracerebral hemorrhage (ICH) model. However, it is not clear if E2 can prevent early hematoma expansion (HE) induced by hyperglycemia in acute ICH. The aim of this study is to evaluate...

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Publicado en:Stroke
Main Authors: Zheng, Yun, Hu, Qin, Manaenko, Anatol, Zhang, Yang, Peng, Yan, Xu, Liang, Tang, Junjia, Tang, Jiping, Zhang, John H
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4308513/
https://ncbi.nlm.nih.gov/pubmed/25523052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.114.006372
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