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Strong Polyadenylation and Weak Pausing Combine To Cause Efficient Termination of Transcription in the Human (G)γ-Globin Gene

The human γ-globin genes form part of a 5-kb tandem duplication within the β-globin gene cluster on chromosome 11. Despite a high degree of identity between the two genes, we show that while the upstream (G)γ-globin gene terminates transcription efficiently, termination in the (A)γ gene is inefficie...

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Detalhes bibliográficos
Main Authors: Plant, Kathryn E., Dye, Michael J., Lafaille, Celina, Proudfoot, Nick J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1069604/
https://ncbi.nlm.nih.gov/pubmed/15798211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.8.3276-3285.2005
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