Phosphorylation of p21 in G(2)/M Promotes Cyclin B-Cdc2 Kinase Activity

Little is known about the posttranslational control of the cyclin-dependent protein kinase (CDK) inhibitor p21. We describe here a transient phosphorylation of p21 in the G(2)/M phase. G(2)/M-phosphorylated p21 is short-lived relative to hypophosphorylated p21. p21 becomes nuclear during S phase, pr...

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Bibliografiske detaljer
Main Authors: Dash, Bipin C., El-Deiry, Wafik S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Gene Expression
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1069593/
https://ncbi.nlm.nih.gov/pubmed/15798220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.8.3364-3387.2005
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