Specific Binding of Tombusvirus Replication Protein p33 to an Internal Replication Element in the Viral RNA Is Essential for Replication

The mechanism of template selection for genome replication in plus-strand RNA viruses is poorly understood. Using the prototypical tombusvirus, Tomato bushy stunt virus (TBSV), we show that recombinant p33 replicase protein binds specifically to an internal replication element (IRE) located within t...

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Detalhes bibliográficos
Main Authors: Pogany, Judit, White, K. Andrew, Nagy, Peter D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1069559/
https://ncbi.nlm.nih.gov/pubmed/15795271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.8.4859-4869.2005
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