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A Substitution in Rous Sarcoma Virus Integrase That Separates Its Two Biologically Relevant Enzymatic Activities

Retroviral integrase prepares viral DNA for integration by removing 2 nucleotides from each end of unintegrated DNA in a reaction referred to as processing. However, it has been known since the processing assay was first described that avian integrases frequently nick 3 nucleotides, as well as 2 nuc...

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Detalles Bibliográficos
Main Authors: Konsavage, Wesley M., Burkholder, Stephen, Sudol, Malgorzata, Harper, Amy L., Katzman, Michael
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1069555/
https://ncbi.nlm.nih.gov/pubmed/15795255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.8.4691-4699.2005
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