Role of Low CD4 Levels in the Influence of Human Immunodeficiency Virus Type 1 Envelope V1 and V2 Regions on Entry and Spread in Macrophages

Human immunodeficiency virus type 1 (HIV-1) isolates vary in their ability to infect macrophages. Previous experiments have mapped viral determinants of macrophage infectivity to the V3 hypervariable region of the HIV-1 envelope glycoprotein. In our earlier studies, V1 and V2 sequences of HIV-1 were...

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Bibliographic Details
Main Authors: Walter, Brandon L., Wehrly, Kathy, Swanstrom, Ronald, Platt, Emily, Kabat, David, Chesebro, Bruce
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1069537/
https://ncbi.nlm.nih.gov/pubmed/15795268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.8.4828-4837.2005
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