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Constitutive Expression of Alpha Interferon by Skin Dendritic Cells Confers Resistance to Infection by Foot-and-Mouth Disease Virus

The role of dendritic cells (DC) in the initiation of immune responses against foot-and-mouth disease virus (FMDV) is poorly understood. We analyzed the innate response of freshly isolated swine skin DC to the virus and show a rapid induction of beta interferon (IFN-β) mRNA but not IFN-α mRNA. Howev...

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Detalhes bibliográficos
Main Authors: Bautista, Elida M., Ferman, Geoffrey S., Gregg, Douglas, Brum, Mario C. S., Grubman, Marvin J., Golde, William T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1069522/
https://ncbi.nlm.nih.gov/pubmed/15795269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.8.4838-4847.2005
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