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Intragenic Suppressors of Induction-Deficient TetR Mutants: Localization and Potential Mechanism of Action

Eight Tn10 Tet repressor mutants with an induction-deficient phenotype and with primary mutations located at or close to the dimer interface were mutagenized and screened for inducibility in the presence of tetracycline. The second-site suppressors with wild-type-like operator binding activity that...

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Detalles Bibliográficos
Publicado en:J Bacteriol
Principais autores: Biburger, Markus, Berens, Christian, Lederer, Thomas, Krec, Traudl, Hillen, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1998
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC106946/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9457882/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.180.3.737-741.1998
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