A novel TetR-regulating peptide turns off rtTA-mediated activation of gene expression.
Conditional regulation of gene expression is a powerful and indispensable method for analyzing gene function. The "Tet-On" system is a tool widely used for that purpose. Here, the transregulator rtTA mediates expression of a gene of interest after addition of the small molecule effector doxycycline....
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| Glavni autori: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science (PLoS)
2014-01-01
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| Serija: | PLoS ONE |
| Online pristup: | http://europepmc.org/articles/PMC4014509?pdf=render |
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