Formation of linear inverted repeat amplicons following targeting of an essential gene in Leishmania

Attempts to inactivate an essential gene in the protozoan parasite Leishmania have often led to the generation of extra copies of the wild-type alleles of the gene. In experiments with Leishmania tarentolae set up to disrupt the gene encoding the J-binding protein 1 (JBP1), a protein binding to the...

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Bibliografiske detaljer
Main Authors: Genest, Paul-André, ter Riet, Bas, Dumas, Carole, Papadopoulou, Barbara, van Luenen, Henri G. A. M., Borst, Piet
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2005
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1069007/
https://ncbi.nlm.nih.gov/pubmed/15781496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki304
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