Pharmacokinetic and Maximum Tolerated Dose Study of Micafungin in Combination with Fluconazole versus Fluconazole Alone for Prophylaxis of Fungal Infections in Adult Patients Undergoing a Bone Marrow or Peripheral Stem Cell Transplant

In this dose escalation study, 74 adult cancer patients undergoing bone marrow or peripheral blood stem cell transplantation received fluconazole (400 mg/day) and either normal saline (control) (12 subjects) or micafungin (12.5 to 200 mg/day) (62 subjects) for up to 4 weeks. The maximum tolerated do...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hiemenz, J., Cagnoni, P., Simpson, D., Devine, S., Chao, N., Keirns, J., Lau, W., Facklam, D., Buell, D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2005
Gaiak:
Pharmacology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1068634/
https://ncbi.nlm.nih.gov/pubmed/15793107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.4.1331-1336.2005
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