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Compensatory Adaptation to the Loss of Biological Fitness Associated with Acquisition of Fusidic Acid Resistance in Staphylococcus aureus

Recent studies have shown that individual amino acid exchanges within elongation factor G (EF-G) cause fusidic acid resistance in Staphylococcus aureus. The data from the present study illustrate that the fusidic acid resistance-mediating amino acid substitutions P406L and H457Y are associated with...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Besier, Silke, Ludwig, Albrecht, Brade, Volker, Wichelhaus, Thomas A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1068613/
https://ncbi.nlm.nih.gov/pubmed/15793122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.4.1426-1431.2005
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