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Pro/con clinical debate: It is acceptable to stop large multicentre randomized controlled trials at interim analysis for futility
A few recent, large, well-publicized trials in critical care medicine have been stopped for futility. In the critical care setting, stopping for futility means that independent review committees have elected to stop the trial early – based on predetermined rules – since the likelihood of finding a t...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2005
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1065108/ https://ncbi.nlm.nih.gov/pubmed/15693981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc3013 |
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