Degradation of the Proapoptotic Proteins Bik, Puma, and Bim with Bcl-2 Domain 3 Homology in Chlamydia trachomatis-Infected Cells

We have previously correlated Chlamydia trachomatis antiapoptotic activity with the blockade of mitochondrial cytochrome c release and the inhibition of Bax and Bak activation. We now report that C. trachomatis infection leads to degradation of Bik, Puma, and Bim, three upstream proapoptotic BH3-onl...

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Main Authors: Dong, Feng, Pirbhai, Mustak, Xiao, Yangming, Zhong, Youmin, Wu, Yimou, Zhong, Guangming
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2005
Assuntos:
Molecular Pathogenesis
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1064967/
https://ncbi.nlm.nih.gov/pubmed/15731089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.3.1861-1864.2005
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