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Broad Degradation of Proapoptotic Proteins with the Conserved Bcl-2 Homology Domain 3 during Infection with Chlamydia trachomatis

Chlamydiae are obligate intracellular bacteria that can inhibit apoptosis of their host cell. As shown recently, this inhibition is in part explained by the proteolytic degradation of the proapoptotic Bcl-2 family members (BH3-only proteins) Bim, Puma, and Bad upon chlamydial infection. In this stud...

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Bibliografiske detaljer
Main Authors: Ying, Songmin, Seiffert, Barbara M., Häcker, Georg, Fischer, Silke F.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1064970/
https://ncbi.nlm.nih.gov/pubmed/15731037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.3.1399-1403.2005
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