Antibody against V Antigen Prevents Yop-Dependent Growth of Yersinia pestis

The V antigen (LcrV) of the plague bacterium Yersinia pestis is a potent protective antigen that is under development as a vaccine component for humans. LcrV is multifunctional. On the bacterial surface it mediates delivery of a set of toxins called Yops into host cells, and as a released protein it...

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Main Authors: Philipovskiy, Alexander V., Cowan, Clarissa, Wulff-Strobel, Christine R., Burnett, Sandra H., Kerschen, Edward J., Cohen, Donald A., Kaplan, Alan M., Straley, Susan C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Microbial Immunity and Vaccines
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1064938/
https://ncbi.nlm.nih.gov/pubmed/15731051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.3.1532-1542.2005
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