Toward a molecular pathogenic pathway for Yersinia pestis YopM

YopM is one of the six “effector Yops” of the human-pathogenic Yersinia, but its mechanism has not been defined. After delivery to J774A.1 monocyte-like cells, YopM can rapidly bind and activate the serine/threonine kinases RSK1 and PRK2. However, in infected mice, effects of Y. pestis YopM have bee...

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Detalhes bibliográficos
Main Authors: Uittenbogaard, Annette M., Chelvarajan, R. Lakshman, Myers-Morales, Tanya, Gorman, Amanda A., Brickey, W. June, Ye, Zhan, Kaplan, Alan M., Cohen, Donald A., Ting, Jenny P.-Y., Straley, Susan C.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2012
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518861/
https://ncbi.nlm.nih.gov/pubmed/23248776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2012.00155
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