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MMP-3 expression and release by rheumatoid arthritis fibroblast-like synoviocytes induced with a bacterial ligand of integrin α5β1

Fibroblast-like synoviocytes (FLSs) play a major role in the pathogenesis of rheumatoid arthritis (RA) by secreting effector molecules that promote inflammation and joint destruction. How these cells become and remain activated is still elusive. Both genetic and environmental factors probably play a...

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Autors principals: Zeisel, Mirjam B, Druet, Vanessa A, Wachsmann, Dominique, Sibilia, Jean
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1064889/
https://ncbi.nlm.nih.gov/pubmed/15642131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1462
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