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MMP-3 expression and release by rheumatoid arthritis fibroblast-like synoviocytes induced with a bacterial ligand of integrin α5β1

Fibroblast-like synoviocytes (FLSs) play a major role in the pathogenesis of rheumatoid arthritis (RA) by secreting effector molecules that promote inflammation and joint destruction. How these cells become and remain activated is still elusive. Both genetic and environmental factors probably play a...

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Detalhes bibliográficos
Main Authors: Zeisel, Mirjam B, Druet, Vanessa A, Wachsmann, Dominique, Sibilia, Jean
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1064889/
https://ncbi.nlm.nih.gov/pubmed/15642131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1462
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