Use of HLA-B27 tetramers to identify low-frequency antigen-specific T cells in Chlamydia-triggered reactive arthritis

Reports of the use of HLA-B27/peptide tetrameric complexes to study peptide-specific CD8(+ )T cells in HLA-B27(+)-related diseases are rare. To establish HLA-B27 tetramers we first compared the function of HLA-B27 tetramers with HLA-A2 tetramers by using viral epitopes. HLA-B27 and HLA-A2 tetramers...

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Autori principali: Appel, Heiner, Kuon, Wolfgang, Kuhne, Maren, Wu, Peihua, Kuhlmann, Stefanie, Kollnberger, Simon, Thiel, Andreas, Bowness, Paul, Sieper, Joachim
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2004
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1064864/
https://ncbi.nlm.nih.gov/pubmed/15535830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1221
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