Hypersensitive K303R oestrogen receptor-α variant not found in invasive carcinomas

INTRODUCTION: Genetic abnormalities or mutations in premalignant breast lesions may have a role in progression toward malignancy or influence the behaviour of subsequent disease. The A908G (Lys303→Arg) change in the gene encoding oestrogen receptor-α (ER-α) creates a hypersensitivity to oestradiol a...

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Bibliografiske detaljer
Main Authors: Davies, Michael PA, O'Neill, Penny A, Innes, Helen, Sibson, D Ross
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2005
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1064111/
https://ncbi.nlm.nih.gov/pubmed/15642159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr965
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