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Structure-Activity Study of the Lantibiotic Mutacin II from Streptococcus mutans T8 by a Gene Replacement Strategy

Mutacin II, elaborated by group II Streptococcus mutans, is a ribosomally synthesized and posttranslationally modified polypeptide antibiotic containing unusual thioether and didehydro amino acids. To ascertain the role of specific amino acid residues in mutacin II antimicrobial activity, we develop...

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Bibliografiska uppgifter
Huvudupphovsmän: Chen, Ping, Novak, Jan, Kirk, Marion, Barnes, Stephen, Qi, FengXia, Caufield, Page W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 1998
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC106391/
https://ncbi.nlm.nih.gov/pubmed/9647795
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