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Effects of Pyruvate Decarboxylase Overproduction on Flux Distribution at the Pyruvate Branch Point in Saccharomyces cerevisiae

A multicopy plasmid carrying the PDC1 gene (encoding pyruvate decarboxylase; Pdc) was introduced in Saccharomyces cerevisiae CEN.PK113-5D. The physiology of the resulting prototrophic strain was compared with that of the isogenic prototrophic strain CEN.PK113-7D and an empty-vector reference strain....

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Main Authors: van Hoek, Pim, Flikweert, Marcel T., van der Aart, Quirina J. M., Steensma, H. Yde, van Dijken, Johannes P., Pronk, Jack T.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC106289/
https://ncbi.nlm.nih.gov/pubmed/9603825
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