The Novel ETS Factor TEL2 Cooperates with Myc in B Lymphomagenesis

The human ETS family gene TEL2/ETV7 is highly homologous to TEL1/ETV6, a frequent target of chromosome translocations in human leukemia and specific solid tumors. Here we report that TEL2 augments the proliferation and survival of normal mouse B cells and dramatically accelerates lymphoma developmen...

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Detalhes bibliográficos
Main Authors: Cardone, Monica, Kandilci, Ayten, Carella, Cintia, Nilsson, Jonas A., Brennan, Jennifer A., Sirma, Sema, Ozbek, Ugur, Boyd, Kelli, Cleveland, John L., Grosveld, Gerard C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1061619/
https://ncbi.nlm.nih.gov/pubmed/15743832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.6.2395-2405.2005
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