Inhibition of RIG-I-Dependent Signaling to the Interferon Pathway during Hepatitis C Virus Expression and Restoration of Signaling by IKKɛ

Interferon (IFN) is one important effector of the innate immune response, induced by different viral or bacterial components through Toll-like receptor (TLR)-dependent and -independent mechanisms. As part of its pathogenic strategy, hepatitis C virus (HCV) interferes with the innate immune response...

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Détails bibliographiques
Auteurs principaux: Breiman, Adrien, Grandvaux, Nathalie, Lin, Rongtuan, Ottone, Catherine, Akira, Shizuo, Yoneyama, Mitsutoshi, Fujita, Takashi, Hiscott, John, Meurs, Eliane F.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2005
Sujets:
Virus-Cell Interactions
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1061556/
https://ncbi.nlm.nih.gov/pubmed/15767399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.7.3969-3978.2005
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