Role of a Cytotoxic-T-Lymphocyte Epitope-Defined, Alternative gag Open Reading Frame in the Pathogenesis of a Murine Retrovirus-Induced Immunodeficiency Syndrome

LP-BM5 murine leukemia virus-infected C57BL/6 mice develop profound immunodeficiency and B-cell lymphomas. The LP-BM5 complex contains a mixture of defective (BM5def) and replication-competent helper viruses among which BM5def is the primary causative agent of disease. The BM5def primary open readin...

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Bibliographic Details
Main Authors: Gaur, Arti, Green, William R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1061551/
https://ncbi.nlm.nih.gov/pubmed/15767431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.7.4308-4315.2005
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