Immunomodulating Effects of HMR 3004 on Pulmonary Inflammation Caused by Heat-Killed Streptococcus pneumoniae in Mice

We investigated the influence of HMR 3004, a new ketolide antibiotic, on the pulmonary inflammation induced by heat-killed fluorescein isothiocyanate-labeled Streptococcus pneumoniae. HMR 3004 downregulated (P < 0.05) the pneumococcus-induced release of interleukin-6 (IL-6), IL-1β, and nitric oxide...

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發表在:	Antimicrob Agents Chemother
Principais autores:	Duong, Michel, Simard, Marie, Bergeron, Yves, Ouellet, Nathalie, Côté-Richer, Mélanie, Bergeron, Michel G.
格式:	Artigo
語言:	Inglês
出版:	American Society for Microbiology (ASM) 1998
主題:	Biologic Response Modifiers
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC106043/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9835535/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.12.3309
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