Immunomodulating Effects of HMR 3004 on Pulmonary Inflammation Caused by Heat-Killed Streptococcus pneumoniae in Mice

We investigated the influence of HMR 3004, a new ketolide antibiotic, on the pulmonary inflammation induced by heat-killed fluorescein isothiocyanate-labeled Streptococcus pneumoniae. HMR 3004 downregulated (P < 0.05) the pneumococcus-induced release of interleukin-6 (IL-6), IL-1β, and nitric oxi...

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Autori principali: Duong, Michel, Simard, Marie, Bergeron, Yves, Ouellet, Nathalie, Côté-Richer, Mélanie, Bergeron, Michel G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 1998
Soggetti:
Biologic Response Modifiers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC106043/
https://ncbi.nlm.nih.gov/pubmed/9835535
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