Serum and Cerebrospinal Fluid Pharmacokinetics of Intravenous and Oral Lamivudine in Human Immunodeficiency Virus-Infected Children

We studied the pharmacokinetics of intravenously and orally administered lamivudine at six dose levels ranging from 0.5 to 10 mg/kg of body weight in 52 children with human immunodeficiency virus infection. A two-compartment model with first-order elimination from the central compartment was simulta...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Mueller, Brigitta U., Lewis, Linda L., Yuen, Geoffrey J., Farley, Maureen, Keller, Amy, Church, Joseph A., Goldsmith, Jonathan C., Venzon, David J., Rubin, Marc, Pizzo, Philip A., Balis, Frank M.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1998
Soggetti:	Antiviral Agents
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC106021/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9835513/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.12.3187
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