Evaluation of Once-Weekly Therapy for Tuberculosis Using Isoniazid plus Rifamycins in the Mouse Aerosol Infection Model

Once-weekly therapy with combinations of isoniazid plus a rifamycin was tested in the mouse low-dose aerosol infection model against two strains of Mycobacterium tuberculosis. Combinations of isoniazid and rifalizil and isoniazid and rifapentine were both highly effective. These animal model data th...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Brooks, Jason V., Orme, Ian M.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1998
Soggetti:	Experimental Therapeutics
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105994/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9797254/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.11.3047
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