Penetration of Clindamycin and Its Metabolite N-Demethylclindamycin into Cerebrospinal Fluid following Intravenous Infusion of Clindamycin Phosphate in Patients with AIDS

Clindamycin, which is usually used in combination with pyrimethamine, has been proven effective in the treatment of cerebral toxoplasmosis in human immunodeficiency virus-infected patients. However, it is not known if clindamycin achieves inhibitory concentrations at the site of infection. Also, it...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Gatti, Giorgio, Malena, Marina, Casazza, Rosetta, Borin, Marie, Bassetti, Matteo, Cruciani, Mario
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Pharmacology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105985/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9797245/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.11.3014
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