Penetration of Clindamycin and Its Metabolite N-Demethylclindamycin into Cerebrospinal Fluid following Intravenous Infusion of Clindamycin Phosphate in Patients with AIDS

Clindamycin, which is usually used in combination with pyrimethamine, has been proven effective in the treatment of cerebral toxoplasmosis in human immunodeficiency virus-infected patients. However, it is not known if clindamycin achieves inhibitory concentrations at the site of infection. Also, it...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Gatti, Giorgio, Malena, Marina, Casazza, Rosetta, Borin, Marie, Bassetti, Matteo, Cruciani, Mario
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1998
Soggetti:	Pharmacology
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105985/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9797245/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.11.3014
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