Gonococcal Resistance to β-Lactams and Tetracycline Involves Mutation in Loop 3 of the Porin Encoded at the penB Locus

penB is a chromosomal mutation that confers resistance to β-lactams and tetracyclines and reduced susceptibility to quinolones in Neisseria gonorrhoeae. It is linked to the porin gene (por) and requires the increased expression of an efflux pump due to mtr. Transformation of a susceptible gonococcus...

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Dades bibliogràfiques

Publicat a:	Antimicrob Agents Chemother
Autors principals:	Gill, M. J., Simjee, S., Al-Hattawi, K., Robertson, B. D., Easmon, C. S. F., Ison, C. A.
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 1998
Matèries:	Mechanisms of Resistance
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105946/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9797206/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.11.2799
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