Pkd1 regulates immortalized proliferation of renal tubular epithelial cells through p53 induction and JNK activation

Autosomal dominant polycystic kidney disease (ADPKD) is the most common human monogenic genetic disorder and is characterized by progressive bilateral renal cysts and the development of renal insufficiency. The cystogenesis of ADPKD is believed to be a monoclonal proliferation of PKD-deficient (PKD(...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Nishio, Saori, Hatano, Masahiko, Nagata, Michio, Horie, Shigeo, Koike, Takao, Tokuhisa, Takeshi, Mochizuki, Toshio
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2005
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1059447/
https://ncbi.nlm.nih.gov/pubmed/15761494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200522850
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