Antitrypanosomal Activity of a New Triazine Derivative, SIPI 1029, In Vitro and in Model Infections

A recently developed diaminotriazine derivative [O,O′-bis(1,2-dihydro-2,2-tetramethylene-4,6-diamino-S-triazin-1-yl)-1,6-hexanediol dihydrochloride; T-46; SIPI 1029] was examined for activity against African trypanosomes in in vitro and in vivo model systems. In vitro, SIPI 1029 was 50% inhibitory f...

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Bibliographische Detailangaben
Hauptverfasser: Bacchi, Cyrus J., Vargas, Marcus, Rattendi, Donna, Goldberg, Burt, Zhou, Weicheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1998
Schlagworte:
Experimental Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC105925/
https://ncbi.nlm.nih.gov/pubmed/9756783
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