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Compartmental Pharmacokinetics and Tissue Drug Distribution of the Pradimicin Derivative BMS 181184 in Rabbits

The pharmacokinetics of the antifungal pradimicin derivative BMS 181184 in plasma of normal, catheterized rabbits were characterized after single and multiple daily intravenous administrations of dosages of 10, 25, 50, or 150 mg/kg of body weight, and drug levels in tissues were assessed after multi...

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Publicado no:Antimicrob Agents Chemother
Principais autores: Groll, Andreas H., Sein, Tin, Petraitis, Vidas, Petraitiene, Ruta, Callender, Diana, Gonzalez, Corina E., Giri, Neelam, Bacher, John, Piscitelli, Stephen, Walsh, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1998
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105922/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9756780/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.10.2700
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