Mechanism of Fluconazole Resistance in Candida krusei

The mechanisms of fluconazole resistance in three clinical isolates of Candida krusei were investigated. Analysis of sterols of organisms grown in the absence and presence of fluconazole demonstrated that the predominant sterol of C. krusei is ergosterol and that fluconazole inhibits 14α-demethylase...

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Main Authors: Orozco, Alison S., Higginbotham, Lindsey M., Hitchcock, Christopher A., Parkinson, Tanya, Falconer, Derek, Ibrahim, Ashraf S., Ghannoum, Mahmoud A., Filler, Scott G.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1998
Fag:
Mechanisms of Resistance
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC105912/
https://ncbi.nlm.nih.gov/pubmed/9756770
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