Mechanism of Fluconazole Resistance in Candida krusei

The mechanisms of fluconazole resistance in three clinical isolates of Candida krusei were investigated. Analysis of sterols of organisms grown in the absence and presence of fluconazole demonstrated that the predominant sterol of C. krusei is ergosterol and that fluconazole inhibits 14α-demethylase...

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Autors principals: Orozco, Alison S., Higginbotham, Lindsey M., Hitchcock, Christopher A., Parkinson, Tanya, Falconer, Derek, Ibrahim, Ashraf S., Ghannoum, Mahmoud A., Filler, Scott G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1998
Matèries:
Mechanisms of Resistance
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC105912/
https://ncbi.nlm.nih.gov/pubmed/9756770
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