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In Vitro and In Vivo Efficacy of the Triazole TAK-187 against Cryptococcus neoformans

Multiple isolates of Cryptococcus neoformans, including those with fluconazole resistance, were tested to assess the in vitro activity of the new triazole TAK-187. MICs of TAK-187 were at least eightfold lower than those of fluconazole, and fungicidal concentrations for most isolates were 4 μg/ml or...

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Autors principals: Schell, Wiley A., De Almeida, Gisele Madeira Duboc, Dodge, Richard K., Okonogi, Kenji, Perfect, John R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC105909/
https://ncbi.nlm.nih.gov/pubmed/9756767
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