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Structure-In Vitro Activity Relationships of Pentamidine Analogues and Dication-Substituted Bis-Benzimidazoles as New Antifungal Agents

Twenty analogues of pentamidine, 7 primary metabolites of pentamidine, and 30 dicationic substituted bis-benzimidazoles were screened for their inhibitory and fungicidal activities against Candida albicans and Cryptococcus neoformans. A majority of the compounds had MICs at which 80% of the strains...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Del Poeta, Maurizio, Schell, Wiley A., Dykstra, Christine C., Jones, Susan, Tidwell, Richard R., Czarny, Agnieszka, Bajic, Miroslav, Bajic, Marina, Kumar, Arvind, Boykin, David, Perfect, John R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1998
Matèries:
Susceptibility
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105869/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9756747/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.10.2495
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